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A Bast Selected Research

7-monohydroxyethylrutoside

12/2011Differences in pharmacological activities of the antioxidant flavonoid monoHER in humans and mice are caused by variations in its metabolic profile.
2/2011The semisynthetic flavonoid monoHER sensitises human soft tissue sarcoma cells to doxorubicin-induced apoptosis via inhibition of nuclear factor-κB.
10/2007The effect of monohydroxyethylrutoside on doxorubicin-induced cardiotoxicity in patients treated for metastatic cancer in a phase II study.
3/2007Anti-inflammatory agents and monoHER protect against DOX-induced cardiotoxicity and accumulation of CML in mice.
2/2007Caspase-dependent and -independent suppression of apoptosis by monoHER in Doxorubicin treated cells.
1/2007Protectors against doxorubicin-induced cardiotoxicity: flavonoids.
12/2003A comparative study between catalase gene therapy and the cardioprotector monohydroxyethylrutoside (MonoHER) in protecting against doxorubicin-induced cardiotoxicity in vitro.
7/2003The new cardioprotector Monohydroxyethylrutoside protects against doxorubicin-induced inflammatory effects in vitro.
4/2003The protective effect of cardiac gene transfer of CuZn-sod in comparison with the cardioprotector monohydroxyethylrutoside against doxorubicin-induced cardiotoxicity in cultured cells.
5/2001Frederine, a new and promising protector against doxorubicin-induced cardiotoxicity.
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A Bast Research Topics

Disease

15Cardiotoxicity
12/2011 - 04/2000
6Inflammation (Inflammations)
12/2017 - 09/2000
4Neoplasms (Cancer)
02/2011 - 05/2001
3Sarcoidosis (Schaumann Disease)
01/2020 - 03/2001
3Asthma (Bronchial Asthma)
05/2012 - 03/2001
2Vomiting
01/2020 - 10/2019
2Weight Loss (Weight Reduction)
01/2020 - 10/2019
2Nausea
01/2020 - 10/2019
2Alcoholic Fatty Liver
12/2015 - 07/2011
2Reperfusion Injury
12/2012 - 01/2012
2Sarcoma (Soft Tissue Sarcoma)
02/2011 - 10/2007
2Lung Diseases (Lung Disease)
09/2001 - 08/2000
1Weight Gain
01/2020
1Ageusia (Hypogeusia)
10/2019
1Pulmonary Fibrosis (Fibrosing Alveolitis)
12/2017
1Cocaine-Related Disorders (Cocaine Addiction)
01/2012
1Ischemia
01/2012
1Non-alcoholic Fatty Liver Disease
07/2011
1Liposarcoma
02/2011
1Small Fiber Neuropathy
12/2008
1Drug-Related Side Effects and Adverse Reactions
12/2007
1Coronary Disease (Coronary Heart Disease)
04/2007
1Ovarian Neoplasms (Ovarian Cancer)
02/2007
1Cardiomyopathies (Cardiomyopathy)
01/2007
1Breast Neoplasms (Breast Cancer)
01/2007
1Hepatocellular Carcinoma (Hepatoma)
01/2005
1Infections
12/2003
1Chronic Obstructive Pulmonary Disease (COPD)
11/2003
1Insulinoma
06/2002
1Type 1 Diabetes Mellitus (Autoimmune Diabetes)
06/2002
1Interstitial Lung Diseases (Interstitial Lung Disease)
09/2001
1Extrinsic Allergic Alveolitis (Hypersensitivity Pneumonitis)
09/2001
1Cardiovascular Diseases (Cardiovascular Disease)
05/2001
1Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
03/2001
1Rheumatoid Arthritis
03/2001
1Heart Diseases (Heart Disease)
11/2000
1Infertility (Sterility)
11/2000

Drug/Important Bio-Agent (IBA)

13Doxorubicin (Adriamycin)FDA LinkGeneric
12/2011 - 04/2000
127-monohydroxyethylrutosideIBA
12/2011 - 04/2000
11FlavonoidsIBA
12/2017 - 04/2000
6AntioxidantsIBA
12/2008 - 11/2000
5Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
05/2012 - 06/2002
3Pharmaceutical PreparationsIBA
01/2020 - 11/2000
3Nitric Oxide (Nitrogen Monoxide)FDA Link
05/2012 - 09/2000
3EnzymesIBA
12/2003 - 09/2000
2NitritesIBA
05/2012 - 09/2007
2Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
01/2012 - 02/2008
2Glutathione (Reduced Glutathione)IBA
10/2007 - 06/2000
2Proteins (Proteins, Gene)FDA Link
11/2003 - 03/2001
2CytokinesIBA
06/2002 - 09/2001
1Methotrexate (Mexate)FDA LinkGeneric
01/2020
1Mycophenolic Acid (Cellcept)FDA LinkGeneric
01/2020
1Azathioprine (Imuran)FDA LinkGeneric
01/2020
1Prednisone (Sone)FDA LinkGeneric
01/2020
1nintedanibIBA
10/2019
1pirfenidoneIBA
10/2019
1QuercetinIBA
12/2017
1Cytochrome P-450 CYP2E1 (CYP2E1)IBA
12/2015
1Reactive Oxygen Species (Oxygen Radicals)IBA
12/2012
1InterferonsIBA
05/2012
1Interleukin-5 (Interleukin 5)IBA
05/2012
1diclofenac hydroxyethylpyrrolidine (DIEP)FDA Link
01/2012
1AnthracyclinesIBA
12/2011
1LipidsIBA
07/2011
13-Iodobenzylguanidine (Iobenguane)IBA
12/2008
1LDL CholesterolIBA
02/2008
1Phytosterols (Plant Sterols)IBA
02/2008
1EstersIBA
02/2008
1CytochromesIBA
12/2007
1antineoplaston A10 (A 10)IBA
10/2007
1Biomarkers (Surrogate Marker)IBA
09/2007
1Indicators and Reagents (Reagents)IBA
09/2007
1IsoprostanesIBA
09/2007
1NitratesIBA
09/2007
1Interleukin-4 (Interleukin 4)IBA
09/2007
18-epi-prostaglandin F2alphaIBA
09/2007
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
09/2007
1Anti-Inflammatory Agents (Anti-Inflammatories)IBA
03/2007
1N(6)-carboxymethyllysine (carboxymethyllysine)IBA
03/2007
1LuteolinIBA
01/2005
1CatalaseIBA
12/2003
1Oxidants (Oxidizing Agents)IBA
11/2003
1Free RadicalsIBA
04/2003
1Streptozocin (Streptozotocin)FDA Link
06/2002
1AlloxanIBA
06/2002
1PeroxiredoxinsIBA
06/2002
1Insulin (Novolin)FDA Link
06/2002
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
09/2001
1BerylliumIBA
09/2001
1frederineIBA
05/2001
1Particulate MatterIBA
05/2001
1NF-kappa B (NF-kB)IBA
03/2001
1TeaIBA
11/2000
1xylometazoline (stas)IBA
09/2000

Therapy/Procedure

5Therapeutics
01/2020 - 11/2000
2Aftercare (After-Treatment)
06/2002 - 11/2000
1Drug Therapy (Chemotherapy)
01/2020
1Free Tissue Flaps
01/2012
1Transcutaneous Electric Nerve Stimulation (TENS)
12/2007
1Mediterranean Diet
04/2007